| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Effects of Silicon Implant with Nanopatterns on Foreign Body Reaction |
| 초록 |
Among all female cancer patients, the proportion of patients with breast cancer is the highest and after breast cancer surgery breast reconstruction is rapidly increasing, and most of these patients have side effects of fibrosis. To suppress the fibrosis, surface modification of breast implants can be applied, one of which is nanopatterned on the implant surface. However, in order to achieve nanopatterning, it is necessary to make a nano-sized mold, which is expensive to manufacture a nano-sized mold. To overcome these shortcomings, nanopatterned breast implants were fabricated using an easy-to-use electrospinning technique and modified imprinting techniques. Also, it has the advantage of non-toxicity by only modifying the physical surface of the breast implant. In addition, nanopatterned breast implants can inhibit the adhesion and activation of fibroblasts and macrophage cells, resulting in the inhibition of fibrosis. |
| 저자 |
최주환1, 조강희1, 홍혜진1, 김세민1, 이경민1, 김혜원1, 신병호2, 허찬녕2, 고원건1
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| 소속 |
1연세대, 2분당서울대병원 |
| 키워드 |
Fibrosis; Nanopattern; Surface modification; Breast Implant; Fibroblast; Macrophage
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| E-Mail |
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