| 초록 |
In this study, A surface grooved conductive scaffold was fabricated by forming aligned grooves to the surface of Poly(Lactic-co-Glycoic acid) (PLGA) scaffold and by coating the poly(pyrrole) conductive polymer. For peripheral nerve regeneration, it is necessary to provide a similar environment in which neurons can grow well to connect damaged nerves. To provide grooves on the surface, poly(vinyl pyrolidone) (PVP) was prepared by electrospinning with aligned fibers, which were then melted in the surface of PLGA scaffold. In addition, optimal conditions for coating the conductive polymer, polypyrrole, on the surface of scaffold were secured and electrical stimulation was optimized. It is expected that this scaffold can be applied to regenerate the nerve tissues naturally in the area of tissue engineering. |
