| 학회 |
한국화학공학회 |
| 학술대회 |
2012년 봄 (04/25 ~ 04/27, 제주 ICC) |
| 권호 |
18권 1호, p.230 |
| 발표분야 |
공정시스템 |
| 제목 |
Kinetic Parameter Estimation of Metabolic Reactions in Clostridium acetobutylicum |
| 초록 |
A kinetic model to describe the dynamic metabolic behavior in Clostridium acetobutylicum ATCC 824 used for acetone-butanol-ethanol (ABE) production is developed by modifying the previously proposed metabolic pathways. We use an efficient optimization algorithm combining a genetic algorithm and an interior point algorithm in order to estimate the kinetic parameters of the model with experimental data, e.g. concentrations of metabolites, glucose and cells, obtained from a batch fermentor. All the parameter sets estimated from the first 36-hour experiment have been verified with the data sets of the additional experiments. This kinetic study will contribute to modifying and improving Clostridium acetobutylicum for enhanced ABE production. |
| 저자 |
김우현1, 엄문호2, 이상현2, 최진달래2, 박선원1
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| 소속 |
1KAIST, 2GS칼텍스 |
| 키워드 |
acetone-butanol-ethanol (ABE) production; Clostridium acetobutylicum; parameter estimation
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| E-Mail |
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| 원문파일 |
초록 보기 |
