화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2021년 봄 (04/21 ~ 04/23, 부산 BEXCO)
권호 27권 1호, p.788
발표분야 이동현상
제목 Synthesis of NIR light-responsivemicro-drug carrier
초록 Light-responsive drug delivery system has been attracted as an external trigger due to its high spatiotemporal control of light dosage. Especially, near-infrared (NIR) light has deep tissue penetration due to minimizing absorption in biological systems which enables various clinical application such as light-responsive drug release. In the light-responsive drug release system, photothermal agent converts light to heat which triggers drug release of the drug carrier. However, most of the light-responsive drug carrier have been developed by nanosized particles which can be easily ejected from the injected area. Therefore, we developed implantable microparticle based of fatty alcohol, IR780, and Doxorubicin. This study showed that the fatty alcohol microparticles were melted under NIR exposure and released the drugs.
저자 엄지연1, 김현웅1, 노윤호1, 심민석2, 봉기완1
소속 1고려대, 2인천대
키워드 이동현상
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