화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터)
권호 36권 1호
발표분야 의료용 고분자
제목 Preparation and characterization of hyaluronic acid/chondroitin sulfate-based hydrogel system using radiation technique
초록 The artificial skin model composed of biocompatible natural polymer and synthetic polymer with high mechanical property were designed for alternative tests to animal experiments. We synthesized hyaluronic acid and chodroitin sulfate derivatives with polymerizable residues with precise control over the substitution degree. The hyaluronic acid/chondroitin sulfate-based hydrogels with various composition were prepared by using radiation technique. The enzymatic degradation kinetics of hydrogel and the drug release properties from hydrogels were investigated to evaluate the feasibility for artificial skin substitutes.
저자 신미래1, 권희정2, 임윤묵2, 노영창2, 김소연1
소속 1충남대, 2원자력(연)
키워드 hydrogel; tissue engineering; skin substitute
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