| 초록 |
Electrospun nanofibers are the most promising scaffolds in the field of tissue engineering due to their three-dimensional structure which is similar to the natural extracellular matrix (ECM). Thus, these have been expected for utilizing effective wound treatment. In this study, we successfully prepared the catechol functionalized nanofibrous patch using gelatin and hyaluronic acid for wound healing scaffolds. The physicochemical and mechanical properties and cell attachments were improved by increasing the content of catechol groups in the patch. Moreover, we also could confirm that the patch can reduce the bleeding from wound and accelerate the wound healing process by animal test. Consequently, it is suggested that our catechol functionalized nanofibrous patch can be used as potential candidates for wound healing and other skin. |
