| 초록 |
Synthesis of formamides from the catalytic carbonylation of amines with CO is of great interest due to their wide applications of formamides as a synthetic intermediates. Up to now, the most commonly used catalysts are either expensive noble metal compounds or difficult-to-handle alkali metal alkoxides. We have found that a solid base, K3PO4 is a highly active and selective catalysts for the amines, producing corresponding formamide in yields up to 99% at relatively mild conditions. Spectroscopic results indicate that such high activity of K3PO4 is closely related to the strong hydrogen bonding ability of PO43- with amino group of an amine, enhancing the nucleophilicity of the amine enough to interact with CO and mediating proton transfer from the amino group to the carbonyl group. |
