화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터)
권호 40권 1호
발표분야 기능성 고분자
제목 Synthesis of Electroconductive Hydrogel Films by Electrically Controlled Click Chemistry for Drug Delivery System
초록 Electroconductive hydrogels are 3-dimensional continuous conducting materials and they are composed by hydrogels and conductive materials. It can be applied to electro-stimulated biomaterials for electro-stimulated systems like biosensors, neural prosthesis and electro-stimulated drug delivery system. In this study, alkyne-functionalized poly(vinyl alcohol) based hydrogel film was deposited on ITO-coated glass electrodes by electro-controlled alkyne–azide cycloaddition, generating Cu(I) catalyst by applying reduction potential of Cu(II) ions. Incorporated carbon nanotubes made the electrical properties of hydrogel improved, so that the electrochemical active area got larger than that of hydrogel without CNTs. The synthesized films were characterized by surface profilometry, UV-vis spectroscopy, and scanning electron microscopy. The electroconduictive hydrogel films were applied to electro-controlled drug delivery system at different pH changing the charge state of drugs
저자 최은정, 정동철, 하성균, 송창식
소속 성균관대
키워드 Electroconductive hydrogel; Electro-click reaction; Drug delivery system
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