화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터)
권호 36권 1호
발표분야 의료용 고분자
제목 A Study on Proliferation and Phenotype of Corneal Endothelial Cells on SIS Sheet
초록 Corneal transplantation is a common transplant procedure performed to improve visual acuity by replacing the opaque. Porcine SIS derived from the submucosal layer of porcine intestine, both generate a minimal inflammatory response following implantation and have been approved for many types of biomedical applications. CEC cells were seeded on SIS sheet. We confirmed morphology of cellular adhesion by scanning electron microscopy. Cell proliferation activity was measured by MTT assay. RT-PCR was conducted to confirm mRNA expression of CEC marker. In the result of MTT assay, cell viability on SIS sheet was higher than plastic bottom. The SIS sheet can act based on this experiment to be very useful to the tissue regeneration. This research was supported by WCU (R31-20029) and SCRC (SC4110)
저자 이가영, 강수지, 조은혜, 이동원, 강길선
소속 전북대
키워드 Corneal Endothelial Cells; Small Intestinal Submucosa
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