| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터) |
| 권호 |
43권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Cross-linkable peptide hydrogel induced by visible light for enhancement of mechanical strength to therapeutic applications. |
| 초록 |
A number of strategies exist to design supramolecular nanomaterials based on self-assembled peptides and their derivatives. These include soft materials based on a varied nanoarchitectures.especially, supramolecular peptide hydrogels offer the fabrication of potential 3D biomaterial scaffolds in tissue engineering due to their remarkable bioactive, biocompatible and biodegradable features. However, these hydrogels have low mechanical properties and are inclined to breakage under a weak disturbance. The mechanical weakness considerably limits the practical therapeutic applications owing to easily erode to water. Therefore, we inoculate the visible light induced cross-linking which is not harmful to living organisms to manipulate peptide hydrogel for enhancement of mechanical strength. The mechanical strength was controlled by the the position of cross-linkable moiety and amino acid sequence.These controlled hydrogels might provide an opportunity to fabricate drug release 3D scaffolds. |
| 저자 |
방우영1, 김인혜1, 정영호2, 한은희2, 이은지3
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| 소속 |
1충남대, 2한국기초과학지원(연), 3광주과학기술원 신소재공학부 |
| 키워드 |
self-assembly; peptide hydrogel; cross-linking
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| E-Mail |
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