| 초록 |
Various 3D printing materials have been applied to bioprinting processes for development of functional tissues and tissue regeneration. In particular, hydrogels that can recapitulate features of extracellular matrix have been widely exploited as 3D printing inks. However, 3D printing of hydrogels has been challenging since stiff hydrogels that are not desirable for cell cultures are required for nice printing fidelity. To overcome this issue, hydrogels formed via guest-host interactions and jammed microgels that exhibit shear-thinning properties were developed and used for bioprinting researches. The hydrogels formed via guest-host interactions were used for fabrication of 3D microchannels within protease-degradable hydrogels and endothelial cells were cultured within the microchannels to mimic 3D blood vessels. Additionally, jammed microgels were developed for 3D printable inks and used for study of endothelial cell migration. |
