| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Comparative study of different tethering of supported lipid bilayers surface coating of implantable biosensing devices |
| 초록 |
Supported lipid bilayers membranes are growing interest as models of biological membranes for coating of implantable biosensing devices. Supported bilayers deposited directly on substrate are separated by a thin film of water. Overcome this limitation, bilayer formation on the tethered surface is the choice. Here, we prepared coated gold substrate with tethered lipid bilayer. Firstly, gold coated glass substrates were tethered by different types of thiol lipids. Secondly, 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) was used for the formation of supported lipid bilayers. The successful surface modification was verified by FT-IR, confocal microscopy and FRAP assay. Antifouling assay was conducted with quartz crystal microbalance with dissipation (QCM-D) apparatus and fluorescence microscopy. The result demonstrates the successful formation of tethered lipid bilayer on gold substrate and provides suitable coating system of implantable biosensing devices |
| 저자 |
Md Lemon Hasan1, Mahmoud A. Elnaggar1, 정윤기2
|
| 소속 |
1Korea Institute of Science and Technology, 2Korea Institute of Science and Technology / Univ. of Science and Technology |
| 키워드 |
Implantable device; tethered lipid bilayer; surface coating; antifouling
|
| E-Mail |
|
