| 초록 |
Electrospinning is a unique technology that can produce non-woven fibrous products. But conventional 2-dimensional inflexible scaffolds have a structural limitation which is not suitable for mimicking extracellular matrix (ECM). Thus, there has been a lot of tries to make 3-dimesional electrospun scaffolds. In our previous study, 3-dimensional ‘clay-like’ scaffolds were fabricated by core-shell electrospinning. Polystyrene (PS) and poly(ε-caprolactone) (PCL) were used in this method and the structure which consists of pure PCL fiber was obtained by selective leaching. Existing fluffy system is deficient in mechanical strength and bio-molecule attachment so it is necessary to complement these characteristics. In this study, dopamine polymerization is used to create physically enhanced fluffy scaffold. To fabricate mechanically enhanced 3-dimensional electrospun scaffolds will promote to variety of soft tissue engineering applications. |
