| 초록 |
Spiropyran are demandable photochromic compounds, which are reversible interconvert between ring-closed colorless spiropyran (SP) and colored ring-opened merocyanine (MC) form. Using these reversible photochromic properties, herein we report Spiropyran with catechol coated PS bead a facile fluorescent delivery matrix. The spiropyran with responsive polymer conjugated therapeutic agents within PS bead perform as a drug matrix, and localized the position of the carrier via cellular imaging. Moreover this system also executes to monitor the real-time cellular uptake present within the cytoplasm. In an arena of bioimaging guided delivery matrix, our reported biocompatible fluorescent carrier appears as novel application for fluorescent probe and to identify the cancer cell through monitoring the cargo release. |
