| 초록 |
Among various wearable devices, a smart contact lens is especially promising for healthcare applications, because it can be used as an excellent platform to facilitate the interface between the human body and an electronic device. However, there has been no report on electrically controlled drug delivery in combination with real-time biometric analysis. Here, we developed a smart contact lens for both continuous monitoring and treatment of diabetic retinopathy. In diabetic model rabbits, we could measure tear glucose levels to be validated by the conventional invasive blood-glucose tests and trigger drugs to be released from reservoirs for the treatment of diabetic retinopathy. Taken together, we successfully demonstrated the first example of smart contact lenses for non-invasive and continuous diabetic diagnosis and diabetic retinopathy therapy. |
