| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터) |
| 권호 |
43권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Stimuli-responsive hydrogel microtubes generated by microfluidic devices for cellular scaffolds |
| 초록 |
In this study, we prepared microfiber and microtube hydrogels by using a microfluidic device with alginate-templated photopolymerization. Alginate templates containing N-isopropylacrylamide (NIPAm) and sodium acrylate (SA) or allyl amine (AA) was irradiated with UV light to invoke in situ photo-polymerization. Poly(NIPAm) is a well-known polymer which exhibited lower critical solution temperature behavior. Furthermore, the addition of SA or AA groups were used to induce the pH responsive property because of the repulsive force by protonation/deprotonation of the acrylate or amine groups, respectively. We found that the stimuli-responsive volume change of the prepared microfibers and mictubes are fully reversible and repeatable. In addition, positively charged surface of the hydrogel micro-objects enhanced the attachment of living cells through the ionic attraction. Furthermore, we found that the number of cells can be increased by further supplying of the nutrient. |
| 저자 |
Kusuma Betha Cahaya Imani1, 윤진환2, 조아라3
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| 소속 |
1Pusan National Univ., 2부산대, 3동아대 |
| 키워드 |
responsive hydrogels; microtubes; microfluidic devices; alginate templating; cell scaffolds
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| E-Mail |
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