| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
대학원생 구두발표 |
| 제목 |
pH-Induced Release Mechanism of Multilayer Thin Films: Neutron Reflectivity (NR) and Quartz Crystal Microbalance (QCM) Study |
| 초록 |
Since layer-by-layer(LbL) assembled multilayer films have advantages to insert active ingredients at desired nanoscale positions within the films, the functional LbL films have been developed for biomedical applications such as drug delivery, controlled release system, and tissue engineering. However, the detailed release mechanism of LbL films has not been well understood in terms of the changes in the internal film structure as well as the release mode of active chains embedded within the film. In the present study, by combining both neutron reflectivity and quartz crystal microbalance, we have systematically investigated the pH-induced release mechanism of multilayer films by adjusting molecular interactions in the film, which are, in turn, related to the types (i.e., strong and weak polyelectrolytes) and the molecular weights of polyelectrolytes. These results give us new insights on the controlled release of target materials from multilayer films. |
| 저자 |
장영선1, 서주연2, Bulent Akgun3, Sushil Satija4, 차국헌1
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| 소속 |
1지능형 유도조합체 연구단, 2에너지 환경 화학융합기술전공, 3화학생물공학부, 4서울대 |
| 키워드 |
polymer multilayer film; release; neutron reflectivity; quartz crystal microbalance
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| E-Mail |
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