초록 |
Emulsion and gas bubble has led to significant progress in multiple area including materials synthesis, ultrasound imaging, and droplet-based high-throughput biological assay. One important challenge that may determine the commercial success and translation of microfluidic technologies is the mass production of monodisperse droplets and bubbles. In this work, we have developed a three-dimensional monolithic elastomer device (3D MED) to enhance the production rate of liquid droplets and gas bubbles. Based on double-sided imprinting technique, 3D microchannels architecture are formed in a monolayer elastomer that has one thousand parallel droplet/bubble generators. Because of the robustness of the microfluidic device, 3D MED could potentially be used for wide applications that require highly monodisperse droplets and bubbles. |