| 초록 |
Copolymer [ethyl acrylate (EA): methyl methacrylate (MMA), 2:1] (Eugragit NE) is widely used in aqueous sustained release coating of pharmaceutical field. However, the film properties of copolymer [EA:MMA, 2:1] (Eugragit NE) is brittle and breakable so it needed to use plasticizer such as propylene glycol. To improve film properties of acryl copolymer, hydroxypropylmethylcellulose (HPMC) is used as a polymeric emulsifier in the redox polymerization in emulsion system of MMA and EA. The synthesis of HPMC resin fortified poly(EA-co-MMA) nanoparticles was carried out by ceric ammonium nitrate (CAN) induced redox polymerization in homogeneous aqueous medium. |
