| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Preparation of multi-channel neural guidance platform and axonal growth control using drug |
| 초록 |
Peripheral Nervous System(PNS) has a limited ability to regenerate after a traumatic injury. Autologous nerve grafts or nerve allografts remain as the current primary treatment method. However, availability of autografts is limited and allografts can cause immunogenic problems. Thus, researchers have developed neural guidance for the nerve regeneration. In this study, as regulating growth of axon is essential for that therapy, we developed a neural guidance testing platform to control the growth of axon using various drugs. We prepared the three-dimensional nerve tissue engineering guidance with the micro-sized hollow channels by using Poly Ethylene Glycol (PEG) as a raw material. Channels are engraved with aligned patterns which mimic a natural extracellular matrix and coated with Polypyrrole (PPy) which is a conductive polymer. Therefore, our scaffolds have structures that give physical and electrical cues for the growth of axon. |
| 저자 |
강성민, 윤병주, 김세민, 이경민, 김지영, 함정우, 고원건
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| 소속 |
연세대 |
| 키워드 |
neural guidance platform; Poly pyrrole
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| E-Mail |
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