| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO)) |
| 권호 |
44권 1호 |
| 발표분야 |
고분자가공/복합재료 |
| 제목 |
Antimicrobial Properties of Photocrosslinked Alginate Hydrogels Containing Silver Nanoparticles |
| 초록 |
Silver nanoparticles (AgNPs) can be highly toxic to bacteria at exceptionally low concentrations while display low toxicity to human cells. Hence, AgNPs become excellent choice as antimicrobial agents in food processing, healthcare and industry in general. One of the best route to further extend the range of applications of antimicrobial metal NPs is by the addition of NPs inside polymer hydrogel matrix. For that purpose, we utilized sodium alginate, a biocompatible polymer, to form antimicrobial hydrogel composite. Here, we introduced methacrylate group into sodium alginate main chain by adding 2-aminoethyl methacrylate into an aqueous solution of sodium alginate containing EDC and NHS. Next, the silver NPs-alginate hydrogels were prepared by dissolving methacrylated alginate in NPs solution and exposed it to the UV light in the present of photoinitiator. Antimicrobial efficacy of the obtained hydrogels with different concentration of NPs were evaluated against Escherichia coli. |
| 저자 |
Maulida Zakia1, 송창현2, 구자민2, 유성일2
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| 소속 |
1Pukyong National Univ., 2부경대 |
| 키워드 |
hydrogel; nanoparticle; alginate; silver; antimicrobial
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| E-Mail |
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