| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Synthesis, Structure, Properties, and Biocompatibility ofNovel Brush Polymers with Phosphorylcholine Bristle |
| 초록 |
New brush polymers with various numbers of bristle ends incorporating phosphorylcholine (PC) moieties are synthesized. The polymers are thermally stable up to 175℃ and form good-quality films with conventional spin-, roll-, and dip-coating, and subsequent drying processes. Interestingly, all these brush polymers, as a PC-containing polymer, demonstrate a stable molecular multi-bilayer structure in thin films that arise due to the efficient self-assembly of the bristles for temperatures ＜55℃ and PC-rich surfaces, and therefore successfully mimic natural cell-membrane surfaces. These novel multi-bilayer structured films repel fibrinogen molecules and platelets from their surfaces but also have bactericidal effects on bacteria. Moreover, the brush-polymer films are found to provide comfortable surface environments for the successful anchoring and growth of HEp-2 cells, and to exhibit excellent biocompatibility in mice. |
| 저자 |
김미희, 이문호, 김가희, 박삼대, 정정운, 김진철, 노예철, 안병철, 진상우, 이택준, 김동민, 권원상, 김경태, 고용기
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| 소속 |
포항공과대 |
| 키워드 |
Brush polymer; phosphocholine; biocompatibility
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| E-Mail |
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