| 학회 | 한국공업화학회 |
| 학술대회 | 2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO)) |
| 권호 | 22권 1호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | Improving Regeneration of Corneal Endothelial Cells by use the Taurine/Silk Fibroin Film |
| 초록 | Taurine (Ta) promote the expression of connective tissue growth factor and it can repair the damaged tissue effectively. So, Ta is suitable for corneal reconstruction from tissue engineering. And, Silk fibroin (SF) is used as a tissue engineering scaffold because of good biocompatibility. In this study, Different ratios of Ta blended film scaffolds were fabricated well with SF. Fabricated Ta/SF films were analyzed using SEM, contact angle, transparency, FTIR, MTT assay, mRNA expression, etc. In results, it can be observed that 0.25mM loaded Ta/SF film have good cell proliferation. Also, Ta/SF film support cell growth and these form hexagonal morphology with well-maintained bio-functions. So, it can be used the Ta/SF film as a suitable alternative for cornea transplantation. This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT & Future Planning(NRF-2017R1A2B3010270) |
| 저자 | 이기원, 강길선 |
| 소속 | 전북대 |
| 키워드 | Taurine; Silk Fibroin; Film; Regeneration of Corneal Endothelial Cells; Scaffold |
