화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 봄 (05/13 ~ 05/14, BEXCO(부산))
권호 14권 1호
발표분야 나노
제목 Investigation of shape-dependent cytotoxicity and immune response of Poly(3,4-ethylenedioxythiophene) Nanomaterials
초록 Poly(3,4-ethylenedioxythiophene) (PEDOT) has received attention as one of the most attractive conducting polymers in bioelectronics. Herein, we focused on the shape-dependent cytotoxicity and immune response in human lung fibroblast (IMR90) and mouse alveolar macrophage (J774A.1) cells. The toxicity of PEDOT nanomaterials was evaluated by cell morphological change, viability, apoptosis, oxidative stress and cytokine release. These results may open a pathway to understanding how to affect the geometrical parameter in cytotoxicity, and offer the evaluation of PEDOT nanomaterials for bioapplication.
저자 김소진, 오완규, 장정식
소속 서울대
키워드 Cytotoxicity; PEDOT; Immune response; Nanomaterials
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