| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
의료용 고분자 부문위원회(초청-영어발표/포스터-국문발표 가능) |
| 제목 |
Chitosan-g-poly(methyl vinyl ketone) nanoporous microspheres for controlled drug delivery system |
| 초록 |
Chitosan(CS) is a well-known natural polysaccharide with good biocompatibility and biodegradability. Grafting modification of chitosan with poly(methyl vinyl ketone)(PMVK) was prepared by free radical method using KPS as an initiator. Methyl vinyl ketone(MVK) was selected as a monomer, because its polymer has photo-degradability. The nanoporous microspheres of graft copolymer were prepared by water-in-oil(W/O) emulsion method using glutaraldehyde(GA) as a crosslinking agent and Tween® 80 as an emulsifier, followed by UV irradiation. The graft copolymer was characterized by FT-IR and thermal methods. SEM shows CS-g-PMVK microspheres are approximately 5 ㎛ and FE-SEM shows microspheres with nanosized pores. |
| 저자 |
김지선, 정일두
|
| 소속 |
부산대 |
| 키워드 |
chitosan; microsphere; drug delivery system
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| E-Mail |
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