| 학회 |
한국공업화학회 |
| 학술대회 |
2012년 봄 (05/09 ~ 05/11, 김대중컨벤션센터) |
| 권호 |
16권 1호 |
| 발표분야 |
정밀화학 |
| 제목 |
Application of thermosensitive hydrogel using Chitosan and Pluronic |
| 초록 |
The adhesion formation after surgical is a significant clinical problem within every surgical specialty. To prevent tissue adhesions, many researchers study them. We prepared thermosensitive hydrogel based on chitosan and pluronic F-127 for adhesion barrier. The aim of the this study was to examined the preparation and characterization of hydrogel formulation composed of pluonic and chitosan. The physicochemical properties of hydrogel were analyzed by gelation time and temperature, viscocity, antimicrobial and scanning electron microscope (SEM) measurement. Also, in vitro experiments correspond well with invivo observationson tissue adhesions. Therefore, the Chitosan/pluronic hydrogel may be the potential to prevent postsurgical adhesions in clinical state. |
| 저자 |
손동희1, 나재운1, 남정표1, 박준규1, 김원석1, 최창용2, 장미경1
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| 소속 |
1순천대, 2다이나믹 |
| 키워드 |
hydrogel; chitosan; pluronic; adhesion
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| E-Mail |
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