화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2012년 봄 (04/12 ~ 04/13, 대전컨벤션센터)
권호 37권 1호
발표분야 의료용고분자 부문위원회
제목 Mussel-Inspired surface chemistry as a new platform for Nitric-Oxide delivery
초록 Nowadays, implant-associated bacterial infection is a potentially serious complication, which leads to the premature implant removal. Although a lot of localized antibacterial agents have been applied to prevent bacterial adhesion/proliferation, the use of antibiotics presents a question about the risk of antibiotic-resistant bacteria. Recently, nitric oxide has been highlighted due to their broad-spectrum antibacterial properties against both gram-positive and gram-negative bacteria. Therefore, nitric oxide (NO) releasing Sol-Gel coating method is being developed as a platform for antibacterial coating. Herein, we proposed some new NO releasing coating technique inspired by mussel, which has smoother surface, thinner thickness, and larger amounts of NO than NO-releasing Sol-Gel method.
저자 김지훈1, 홍선기2, 신재호3, 이해신2, 김원종1
소속 1포항공과대, 2한국과학기술원 화학과, 3광운대
키워드 nitric oxide; mussel; surface chemistry
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