화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터)
권호 43권 1호
발표분야 의료용 고분자 부문위원회 I
제목 Development of multi-needle device for  intradermal vaccination of FMD vaccine
초록 In this study, a novel multi-needle (MTN) device was developed for intradermal vaccination of foot-and-mouth disease vaccine. The MTN device was compared with the traditional intramuscular vaccination and needleless device (IDAL®) for intradermal administration. The PI value in MTN vaccinated pigs (47+6) with 0.3ml is comparable with intramuscularly vaccinated pigs (57+11) immunized with 2 ml. PI value of MTN vaccinated pigs was also significantly different with IDAL® vaccinated pigs at 14+4. Cows immunized using the MTN device showed superior VNT compared to other groups. Overall, the MTN device provides protection against FMD with a 6.6 fold dose sparing.
저자 정성동1, 이광녕2, 김유천1
소속 1한국과학기술원, 2검역검사본부
키워드 multi-needle device; vaccine; intradermal immunization
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