학회 |
한국고분자학회 |
학술대회 |
2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터) |
권호 |
43권 1호 |
발표분야 |
의료용 고분자 부문위원회 I |
제목 |
Development of multi-needle device for intradermal vaccination of FMD vaccine |
초록 |
In this study, a novel multi-needle (MTN) device was developed for intradermal vaccination of foot-and-mouth disease vaccine. The MTN device was compared with the traditional intramuscular vaccination and needleless device (IDAL®) for intradermal administration. The PI value in MTN vaccinated pigs (47+6) with 0.3ml is comparable with intramuscularly vaccinated pigs (57+11) immunized with 2 ml. PI value of MTN vaccinated pigs was also significantly different with IDAL® vaccinated pigs at 14+4. Cows immunized using the MTN device showed superior VNT compared to other groups. Overall, the MTN device provides protection against FMD with a 6.6 fold dose sparing. |
저자 |
정성동1, 이광녕2, 김유천1
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소속 |
1한국과학기술원, 2검역검사본부 |
키워드 |
multi-needle device; vaccine; intradermal immunization
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E-Mail |
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