| 초록 |
Bio-based polyurethane (BPU) has been developed using a castor oil/poly(ε-caprolactone) hybrid polyol, and antibacterial BPU nanofiber containing triclosan-cyclodextrin (TR-CD) complexes were successfully fabricated using an electrospinning process. The α-, β-, and γ-types of CDs were tested for the formation of TR-CD complexes and the structural and thermal characteristics of TR-CD complexes were investigated. After the encapsulation of TR-CD complexes in BPU nanofiber, the effect of TR-CD complexes on the thermal stability, mechanical properties, and releasing ability of BPU nanofiber was evaluated. The antibacterial properties of the resulting BPU/TR-CD nanofibers were also investigated against Gram-positive and Gram-negative bacteria. This BPU/TR-CD nanofiber may be a potential candidate for biomedical applications. This research was supported by Korea Institute for Advancement of Technology (KIAT) (N0000993) and National Research Foundation of Korea (NRF-2015M3C8A6A06014792). |
