| 학회 |
한국공업화학회 |
| 학술대회 |
2005년 가을 (10/28 ~ 10/29, 건국대학교) |
| 권호 |
9권 2호 |
| 발표분야 |
고분자 |
| 제목 |
Reduction of postsurgical adhesion formation with carboxymethyl chitosan hydrogels synthesized by radiation |
| 초록 |
Biocompatible and biodegradable hydrogels based on carboxymethyl chitosan (CM-chitosan) were prepared as physical barriers for preventing surgical adhesions. These interpolymeric hydrogels were synthesized by the gamma irradiation crosslinking technique. A 1.5 cm × 1.5 cm of cecal serosa and an adjacent abdominal wall were abraded with bone burr until the serosa surface was disrupted and hemorrhagic but not perforated. The denuded wall was covered with either CM-chitosan hydrogels or solutions from the CM-chitosan hydrogel. Control rat serosa was not covered. Nine days later, the rats were sacrificed and the adhesion was scored on a 0～5 scale. |
| 저자 |
박경란, 임윤묵, 전준표, 노영창
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| 소속 |
한국원자력(연) |
| 키워드 |
postsurgical adhesion; carboxymethyl chitosan; hydrogels; radiation
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| E-Mail |
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