| 학회 |
한국공업화학회 |
| 학술대회 |
2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 |
24권 1호 |
| 발표분야 |
포스터-정밀화학 |
| 제목 |
Fabrication of Monodisperse and Mechanically Controllable PEG -Acrylated Microgel beads for Solid-Phase Peptide Synthesis |
| 초록 |
Droplet microfluidics combined with addition polymerization of acrylate monomers is an attractive technology to control micro-scaled skeletal architecture.[1] Recently, there are widespread reports of PEG hydrogels that is suitable for water compatiblility and anti-fouling.[2] In this study, microgel beads prepared from poly(ethylene glycol) methyl ether acrylate (PEGA) and poly(ethylene glycol) diacrylate (PEGDA) are characterized for mechanical properties. This mechanically controllable PEG hydrogel bead was successfully performed for solid -phase peptide synthesis. The loading level and purity of tripeptides were evaluated to evaluate coupling efficiency. The synthesis and application of SPPS is described in order to offer the suitable technology of pharmaceutical ingredient production. |
| 저자 |
김성수1, 이상명2, 신동식3
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| 소속 |
1강원대, 2CANTIS, 3숙명여자대 |
| 키워드 |
Microfluidic chip; Droplet; Hydrogel; PEG; Solid-Phase Peptide Synthesis
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| E-Mail |
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