화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2007년 가을 (11/02 ~ 11/03, 한경대학교)
권호 11권 2호
발표분야 정밀화학
제목 A study on N-amido-3,3-diflouro-2-pyrrolidone derivatives: Synthesis & NO Inhibition Effects s on RAW264.7 Cell
초록 N-amido-3,3-diflouro-?2 -pyrrolidone derivatives were synthesized from ethyl 2,2-difluoro-4-iodo-4-(trimethylsilyl) butanolate and various hydrazides, and screened for their inhibitory effect on Nitric oxide and cell viability in murine macrophage RAW 264.7 cells stimulated with lipopolysaccharide (LPS).
저자 하영애1, 김기선2, 곽경철1, 채규윤1
소속 1원광대, 2대불대
키워드 N-amido-3; 3-diflouro- 2-pyrrolidone; ethyl-2; 2-difluoro-4-iodo-4-(trimethylsilyl)butanolate; NO-inhibition effect; Anti-inflammation
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