학회 | 한국공업화학회 |
학술대회 | 2007년 가을 (11/02 ~ 11/03, 한경대학교) |
권호 | 11권 2호 |
발표분야 | 정밀화학 |
제목 | A study on N-amido-3,3-diflouro-2-pyrrolidone derivatives: Synthesis & NO Inhibition Effects s on RAW264.7 Cell |
초록 | N-amido-3,3-diflouro-?2 -pyrrolidone derivatives were synthesized from ethyl 2,2-difluoro-4-iodo-4-(trimethylsilyl) butanolate and various hydrazides, and screened for their inhibitory effect on Nitric oxide and cell viability in murine macrophage RAW 264.7 cells stimulated with lipopolysaccharide (LPS). |
저자 | 하영애1, 김기선2, 곽경철1, 채규윤1 |
소속 | 1원광대, 2대불대 |
키워드 | N-amido-3; 3-diflouro- 2-pyrrolidone; ethyl-2; 2-difluoro-4-iodo-4-(trimethylsilyl)butanolate; NO-inhibition effect; Anti-inflammation |