| 학회 |
한국공업화학회 |
| 학술대회 |
2006년 가을 (11/10 ~ 11/11, 경희대학교(수원캠퍼스)) |
| 권호 |
10권 2호 |
| 발표분야 |
콜로이드계면화학 |
| 제목 |
Self-assembled Nanoparticle of poly(amino acid)s with α-helices and Targeted system for cancer therapy |
| 초록 |
Novel amphiphilic graft copolymers composed of poly(2-hydroxyethyl aspartamide) (PHEA) as the hydrophilic backbone and oligo(L-leucine) as the grafted hydrophobic chain were successfully synthesized by a ring-opening polymerization of the Leu-NCA to backbone polymer. The amphiphilic graft copolymer formed nano-sized self-assemblies with unique morphology in aqueous solution. The hydrophobic domains can adopt regular conformations that are insoluble in water, namely, rod-like α-helices for oligo(L-leucine). |
| 저자 |
정재현1, 강윤정1, 조용우2, 김종득1
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| 소속 |
1한국과학기술원, 2한양대 |
| 키워드 |
Poly(amino acid)s; self-assembly; Targeted system
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| E-Mail |
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