| 초록 |
The morphology of ultrafine fibers produced by electrospinning method strongly depends on the spinning conditions such as polymer concentration, spinning distance, additive-type and volatility of solvent. The addition of additives to spinning solution could be expected to be an important parameter influencing the morphology of fibers collected on target, because the additives change the physicochemical properies of polymer solution including the surface tension. Biodegradable aliphatic polyesters like poly(3-hydroxybutyrate), PHB, are of particular interest for biomedical applications such as suture or implant materials, in drug delivery, and most recently for tissue engineering. The aim of this study is to investigate the effect of organosoluble electrolyte on the diameter of electrospun PHB ultrathin fibers. The variation in polymer concentration, spinning distance, and electric field did not show any significant effect on the average fiber diameter. However, the addition of benzyl triethylammonium chloride (BTEAC) to polymer solution caused a significant decrease of fiber diameter of PHBV fibers by an oder of magnitude down to approximately 0.8 μm. In addition, BTEAC caused significant variation of PHBV/chloroform solution properties. The electrical conductivity of the solution was increased by several order of magnitude by addition of BTEAC and the surface tension increased gradually with increasing amount of BTEAC, while no significant change was observed for the solution viscosity.
|
