초록 |
Blended natural polymers composed of chitosan (Cs) and gelatin (G) with various composition ratio were produced as candidate materials for biomedical application. Novel cross-linked sponges compared of gelatin/chitosan 100/0 90/10 70/30 30/70 10/90 0/100 and different amounts of genipin concentration (3, 1, and 0.1 wt%). Genipin was used to crosslinking agent of gelatin/chitosan blends, promoting the formation of primary amine and tertiary amine between chitosan and gelatin, or by itself. The SEM analysis showed that the pore size of gelatin/chitosan sponge was increased with increasing blend ratio of chitosan. As the chitosan content in the sponge increased, the porosity increased, resulting in enhanced water uptake ability. The ATR-FTIR showed that the amount of amine group of gelatin/chitosan was decreased with increasing genipin concentration. |