화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2008년 가을 (10/09 ~ 10/10, 일산킨텍스)
권호 33권 2호
발표분야 의료용 고분자 부문위원회
제목 Preparation of Gelatin/Chitosan Sponge using Genipin forWound Healing.
초록 Blended natural polymers composed of chitosan (Cs) and gelatin (G) with various composition ratio were produced as candidate materials for biomedical application. Novel cross-linked sponges compared of gelatin/chitosan 100/0 90/10 70/30 30/70 10/90 0/100 and different amounts of genipin concentration (3, 1, and 0.1 wt%). Genipin was used to crosslinking agent of gelatin/chitosan blends, promoting the formation of primary amine and tertiary amine between chitosan and gelatin, or by itself. The SEM analysis showed that the pore size of gelatin/chitosan sponge was increased with increasing blend ratio of chitosan. As the chitosan content in the sponge increased, the porosity increased, resulting in enhanced water uptake ability. The ATR-FTIR showed that the amount of amine group of gelatin/chitosan was decreased with increasing genipin concentration.
저자 배민수1, 정성인2, 김성은1, 권일근2
소속 1경희대, 2구강생물학(연)
키워드 genipin; gelatin; chitosan; sponge; wound healing
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