| 학회 |
한국화학공학회 |
| 학술대회 |
2009년 봄 (04/23 ~ 04/24, 광주 김대중컨벤션센터) |
| 권호 |
15권 1호, p.865 |
| 발표분야 |
재료 |
| 제목 |
Application of BBOT-doped silica nanoparticles in bioimaging |
| 초록 |
Blue light emitting silica nanoparticles with very low toxicity were fabricated using ultrasound-assisted Stber method. Formation of nanoparticles was promoted by large amount of energy from collapse of microbubbles generated by ultrasound. Morphological and photoluminescent properties of BBOT-doped silica nanoparticles prepared by this method were examined by field emission scanning electron microscope (FE-SEM) and fluorescence spectrometer, respectively. Fabricated nanoparticles showed bright blue photoluminescence in solid form and nanoparticles dispersed in aqueous solvent also showed strong emission. Photoluminescent emission of BBOT-doped silica nanoparticles was located in the emission range of BBOT. From this, existence of BBOT in silica nanoparticle was verified. To test toxicity of nanoparticles, HeLa cells were incubated with amino-functionalized nanoparticles and cell viability was measured. Presence of nanoparticles at intracellular region was visualized by confocal microscopy. The potential application of BBOT-doped silica nanoparticles for bioimaging will be discussed. |
| 저자 |
위린복1, 이경균1, 민정선2, 김진철2, 이상근3, 윤선홍3, 안정근2, 김도현4
|
| 소속 |
1한국과학기술원, 2충남대, 3한국조폐공사, 4한국과학기술원 / 초미세화학공정시스템 연구센터 |
| 키워드 |
dye-doped silica; sonochemistry; bioimaging
|
| E-Mail |
|
| 원문파일 |
초록 보기 |
