| 학회 |
한국공업화학회 |
| 학술대회 |
2006년 봄 (05/12 ~ 05/13, 전북대학교) |
| 권호 |
10권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Application and Characterization of Thermosensitive Poly(N-isopropylacrylamide-b-ε-caprolactone) Nanoparticles |
| 초록 |
To investigate thermosensitive polymeric nanoparticle, amphiphilic block copolymers of poly(N-isopropylacrylamice)-b-poly(ε-caprolactone) synthesized by hydroxy-terminated poly(N-isopropylacrylamide) initiated ring opening polymerization of ε-caprolactone. The characterizations of PNPCL nanoparticles showed PCL block length dependent physicochemical characters such as particle sizes, CAC, and hydrophobicities. The drug release tests revealed that the formation of thermosensitive hydrogel layer resulted in the enhanced sustained drug release patterns by acting as an additional diffusion barriers. |
| 저자 |
장학수, 최창용, 채수영, 박준규, 장미경, 나재운
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| 소속 |
순천대 |
| 키워드 |
thermosensitive; drug delivery system
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| E-Mail |
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