| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
대학원생 구두발표 |
| 제목 |
Multi-functional Nanocarriers Based on Calcium Phosphate Coated Gold Nanoparticles for Cancer Therapy |
| 초록 |
Multi-functional nanocarriers for theragnostics are focused recently and a number of nanocarriers have been developed. Metallic and inorganic nanoparticles are attractive materials for thergnostic nanocarriers due to their unique properties such as size- and shape-dependent optoelectronic properties, high X-ray absorption and magnetic properties. In spite of numerous advantages, inorganic nanoparticle has limitations to use for nanocarriers because of their structural characteristics and a number of researches are in progress to overcome this limitation. Herein, we described the fabrication method of core-shell nanoparticles for nanocarrier based on gold nanoparticle and calcium phosphate. Drug was successfully encapsulated in the pH-responsive, nonagglomerating, nontoxic calcium phosphate layer and the delivery pathway and accumulation of drug loaded nanoparticles evaluated by X-ray CT using gold nanoparticle core. |
| 저자 |
차의준1, 선인철2, 김영일1, 이상천3, 김광명2, 권익찬2, 안철희1
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| 소속 |
1서울대, 2한국과학기술(연), 3경희대 |
| 키워드 |
Multi functional; calcium phosphate; gold; nanoparticle
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| E-Mail |
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