| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Synthesis of Functionalized Star-shaped Poly(ethylene glycol) UsingAnionic Polymerization Method for Biomedical Applications |
| 초록 |
Star-shaped Poly(ethylene glycol)s (PEG)s have been developed for various applications in biomedical and pharmaceutical areas. Their smaller hydrodynamic volume and spherical shape allow them to have more efficient anti-fouling properties in comparison to linear PEGs. Star-shaped PEG was synthesized by anionic polymerization in DMSO using diphenylmethyl potassium (DPMK) as a strong base catalyst. Anionic polymerization is the most powerful method to obtain well defined structure. Star-shaped PEG with the molecular weight of 80 K was obtained and the molecular weight distribution was narrower than 1.03. For application to biomedical areas, terminal groups were functionalized with amino groups via chain transfer reaction. Finally, Natural-inspired adhesion agents were introduced into the chain ends of star-shaped PEG. |
| 저자 |
김주은1, 허정윤1, 정지헌1, 변영로1, 김정안2, 안철희1
|
| 소속 |
1서울대, 2경희대 |
| 키워드 |
Star-shaped PEG; anionic polymerization
|
| E-Mail |
|
