| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
고분자합성-구조제어중합 |
| 제목 |
Synthesis of Dendritic Poly(ethylene glycol) UsingAnionic Polymerization Method for Biomedical Applications |
| 초록 |
Poly(ethylene glycol)s (PEG)s have been developed for anti-fouling materials that prevent absorption of non-specific proteins at the surface in biomedical and pharmaceutical areas. To improve anti-fouling efficiency, dendritic PEGs were synthesized by living anionic ring opening polymerization of ethylene oxide. Anionic polymerization is the most powerful method to obtain well defined structure. Dendritic PEGs were synthesized by divergent method and each generation was carried out in THF using diphenylmethyl potassium (DPMK) catalyst. Allyl bromide was introduced to polymeric chain ends and dihydroxylation was carried out for branch point. Focal point and end groups were functionalized for biomedical application. All generations were characterized by 1H NMR spectroscopy and GPC. |
| 저자 |
김주은1, 강정규1, 변영로1, 김정안2, 안철희1
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| 소속 |
1서울대, 2경희대 |
| 키워드 |
Dendrimer; PEG; antifouling
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| E-Mail |
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