| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Fabrication of the Surface-Nanogrooved Scaffold to mimic the Nerve Microenvironment for Regeneration of the Nerve Cells |
| 초록 |
This study presents the surface-fiber-assisted scaffold for mimicking the nerve-specific extra-cellular matrix to differentiate the nerve stem cells. To recover the nerve cells, the new treatment using nerve stem cells has been researched and it is important to research the nerve-specific scaffold which is capable of differentiating the nerve stem cells effectively in the tissue engineering area. By this necessity, many techniques to produce the structure which forms the surroundings to make cell alignment, differentiation, and migration have been carried out. In this work, PLGA (poly(lactide-co-glycolide)) is used as the supporter, and PEO (poly(ethylene glycol)) fibers are adapted to fabricate grooves on a surface to construct the optimal conditions of cell activity. It is expected that this scaffold can be applied to guide the effective nerve regeneration method in the tissue engineering area. |
| 저자 |
고원건, 방혜정, 김민수, 정의석, 한상원, 민지홍
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| 소속 |
연세대 |
| 키워드 |
Scaffold; Nerve; Microenvironment
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| E-Mail |
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