| 초록 |
Cefpodoxime proxetil (CPD) was crystallized by using an Aerosol Solvent Extraction System (ASES) with supercritical CO2, where the particle size and morphology was investigated according to CPD solution concentration, solvent type, and mass ratio between CPD solution and sc-CO2. The particles were analyzed by a Scanning Electron Microscopy (SEM), which showed that the size of primary particle was measured to be 100~200 nm and the morphology is similar to spherical type. The size of secondary particle was about 300~600 nm as a result of primary particle agglomeration. |
