| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Development of Bacterial Driven Micro Beads for Targeted Anti-cancer Therapy |
| 초록 |
Hydrogels are one of the most ideal materials for the biomedical application owing to their ability to absorb a large volume of water within in their structure. They also have a highly porous structure which aids in the steady and controlled release of the drug. Our goal is to develop bacterial driven micro-beads which would deliver the drugs inside the tumour and degrade it from inside out. These bio-actuated devices have a wide variety of application in medical field including targeted drug delivery into the tumour. In this work we have developed bacterial driven micro-bead containing the anti-tumour drug loaded nanoparticles inside as the cargo. In order to have the micro-bead, the tumour targeting capabilities we have attached genetically engineered Salmonella Typhimurium bacteria onto the surface of beads. These bacteria have a dual purpose of both tumour targeting and providing the propulsion force to the micro-beads. |
| 저자 |
박석호1, 조성훈1, 박인규1, Saji Uthaman2
|
| 소속 |
1전남대, 2Chonnam National Univ. |
| 키워드 |
Hydrogel; Nanoparticles; Bacteria; Microbead; Targeting
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| E-Mail |
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