화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션)
권호 20권 1호
발표분야 생체재료_포스터
제목 Preparation and Characteristic of Thermo-sensitive Chitosan-F127-Chitosan Tri-block Copolymer as Scaffold for Cell delivery
초록 In this study, we synthesized thermo-sensitive chitosan–F127-chitosan tri-block copolymer by radical polymerization. The tri-block copolymers has a property of sol-gel phase transition in particular temperature. The chitosan of narrow molecular weight distribution was prepared by ultrafilteration method. The characterization of triblock copolymer were analyzed by 1H NMR, FT-IR and SEM. The triblock copolymer showed that it was occurred sol-gel phase transition at certain temperature by hydrophobic-hydrophilic moiety balance. These results suggest that chitosan-F127-chitosan tri-block copolymer can apply biomaterial field such as scaffold for cell delivery. This work was supported by the National Research Foundation of Korea(NRF) grant funded by the Ministry of Science, ICT & Future Planning. (NRF-2014R1A2A1A10053027).
저자 최선주, 최창용, 나재운
소속 순천대
키워드 Chitosan; F127; Thermosensitive hydrogel tri-block copolymer; cell delivery
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