초록 |
Recent studies have sought to chemically control and tailor the metabolic behaviors of non-spore-forming cells, as well as enhancing their viability against adverse environmental conditions, by forming thin (< 100 nm), tough artificial shells. These living “cell-in-shell” structures, called artificial spores (chemically-formed spore-like structures), enable control of cell division, protection against physical and chemical stresses, and cell-surface functionalizability, as well as providing the cells with exogenous properties that are not innate to the cells but are introduced chemically, such as magnetism, heat-tolerance, and UV-resistance. In this talk are discussed chemical approaches to individually encapsulate living cells within thin and tough shells, such as inorganic silica and organic polydopamine shells, with the aim of creating artificial spores. |