화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2014년 봄 (04/30 ~ 05/02, 제주국제컨벤션센터)
권호 18권 1호
발표분야 포스터-생물공학
제목 Effects of Dietary Fiber from Mozuku(Cladosiphon novae-caledoniae kylin) Residue on Antioxidant Activity and Anticancer in Human Colon Cancer Cells According to Extraction Condition
초록 In this study, the dietary fiber contents of Mozuku residue and the extraction condition of the dietary fiber was investigated. And the amount of the total polyphenols and flavonoids in the dietary fiber from Mozuku residue was measured and anticancer effects were verified through growth inhibition in human colon cancer cells. The total dietary fiber content of Mozuku residue was 72.2%. It was effective to extract soluble dietary fiber with 1.5% Na2EDTA and 0.05N HCl in Mozuku residue. Also, the extraction time and temperature affected the yields of solube dietary fiber. The contents of total polyphenols and flavonoids were the highest in 1% NaOH extract. In the result of viability in human colon cancer cells, growth inhibition on HT-29 cells was observed in D.W., 0.05N HCl, and 0.5% Na2CO3 extracts in a dose-dependent manner.
저자 정행순, 최민경, 이재화
소속 신라대
키워드 Mozuku residue; dietary fiber; antioxidant; anti-cancer; human colon cancer
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