| 학회 |
한국화학공학회 |
| 학술대회 |
2017년 가을 (10/25 ~ 10/27, 대전컨벤션센터) |
| 권호 |
23권 2호, p.1758 |
| 발표분야 |
생물화공 |
| 제목 |
Immobilization of an antimicrobial peptide on solid substrates via initiated chemical vapor deposition (iCVD) |
| 초록 |
We developed a simple and efficient method for the immobilization of a potent AMP on the surface of solid supports via initiated chemical vapor deposition (iCVD). The surface of the slide glass was functionalized with vinyl-containing polymer by iCVD, and Cys-linked AMP peptides could be immobilized on the functionalized surface via simple thiol-ene click chemistry with high efficiency. The antimicrobial efficacy of the immobilized peptides was investigated against pathogenic bacteria including Staphylococcus aureus and it was revealed that AMP-GS-Cys exhibited high antibacterial efficacy (＞96%). |
| 저자 |
김상현1, 정구민1, 성혜정1, 성봉현2, 임성갑1, 김선창1, 정기준1
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| 소속 |
1KAIST(한국과학기술원), 2KRIBB(한국생명공학(연) |
| 키워드 |
생물화공 |
| E-Mail |
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| 원문파일 |
초록 보기 |
