| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO)) |
| 권호 |
44권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Ternary nanofiber matrices composed of PCL/Black Phosphorus/Collagen to enhance osteodifferentiation |
| 초록 |
The nanofiber matrices using electrospinning have been actively studied in biomedical and tissue engineering application fields. The electrospinning is an effective method for to produce a three-dimensional porous structure which is similar to the natural extracellular matrix. Black phosphorus (BP) is a layered structure of 2D materials consisting phosphorus elements which is an inorganic component that constitutes the bones of the human body. Poly(ε-caprolactone) (PCL) is a one of biodegradable polymers and it can be fabricated easily. Collagen (Col) has the ability to increase the hydrophilicity and is a major component of the natural ECM. We concentrate on fabrication of ternary nanofiber matrices composed of PCL, BP and Col. Fabricated matrices can promote the osteogenic differentiation of preosteoblasts without hampering their proliferation. These results indicate that the PCL/BP/Col nanofiber matrices can be a promising candidate as scaffolds for Bone tissue engineering. |
| 저자 |
이유빈1, 송수진1, 강문성1, 이현욱2, 현승휴3, 한동욱1
|
| 소속 |
1부산대, 2한국기초과학지원(연), 3가고시마대 |
| 키워드 |
Nanofiber matrices; Polycaprolactone; Black phosphorus; Osteodifferentiation; Bone tissue engineering
|
| E-Mail |
|
