| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 봄 (04/12 ~ 04/13, 서울대학교) |
| 권호 | 27권 1호, p.272 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Preparation and Characterization of Small Intestine Submucosa Impregnated Injectable Hydrogels for Tissue Engineering |
| 초록 | Recently, tissue engineering approaches using injectable, in situ gel-forming systems have been reported. A injectable formulations offer specific advantages over preformed scaffolds such as: possibility of a minimally invasive implantation, an ability to fill a desired shape, and easy incorporation of various therapeutic agents. Injectable polymer formulation can gel in vivo in response to temperature change (thermal gelation), pH change, ionic cross-linking, or solvent exchange. The objective fo this study was to prepare small intestine submucosa (SIS) impregnated injectable hydrogels (poloxamer, methylcellulose, and alginate) for tissue engineering. The SIS was isolated from porcine intestine. It is primarily an acellular extracellular matrix material and can induce tissue remodeling because of the various growth factors. Turbidity measurements of hydrogels were made on a spectrophotometer for gelation. Acknowledgment: This work was supported by MOCIE. |
| 저자 | 최진산1, 이상진*2, 강길선3, 이영무*4, 이일우**, 이해방*** |
| 소속 | 1전북대, 2*한양대, 3**가톨릭의과대, 4***한국화학(연) |
| 키워드 | |
