| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터) |
| 권호 |
36권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Electrospun poly(L-lactide-co-ε-caprolactone) nanofibers coated withcalcium phosphate for tissue engineering |
| 초록 |
This study is to develop an efficient process to provide electrospun poly(L-lactide-co-ε-caprolactone) (PLCL) fibers with a bone-like calcium phosphate (CaP). Firstly, the PLCL was fabricated by electrospinning. Then, the fibers were immersed in simulated body fluid (SBF) to mineralize for varying time periods (1, 3, 5, 7 and 14 days). The PLCL fibers coated with the CaP were characterized by using x-ray diffraction (XRD), scanning electron microscopy (SEM) and fourier transform spectroscopy (FT-IR). Biocompatibility of the CaP coated PLCL fibers were confirmed the biocompatibility by the water contact angle, cell cytotoxicity and fluorescence microscopy measurement and the PLCL fibers are expected to have a potential possibility as the natural bone in bone tissue engineering. |
| 저자 |
임윤묵1, 조선영1, 김용수2, 김우진1, 권희정2, 박종석1, 신흥수2, 노영창1
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| 소속 |
1한국원자력(연), 2한양대 |
| 키워드 |
electrospinning; calcium phosphate; simulated body fluid; PLCL; nanofiber
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| E-Mail |
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